on all orders above $300.00

FREE Pills!


for free with every order



Less than in your
local pharmacy

Search by letter:


Enter coupon: (if you have one)


Acyclovir is one of the oldest drugs used to treat herpes simplex viruses and remains the first line of treatment for these infections. Acyclovir is available as a generic, made by several companies, or under the brand name Zovirax, made by GlaxoSmithKline and available in tablet, capsule, and liquid form.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

Similar Products:
Lipofin, Perdamel, Gastrozol, Tizanidina, Refluyet, Tadalafil, Alsartan, Noroclav, Metindol, Lotrial, Effekton, Aldoc, Telfast, Eslorex, Indocap, Duloren, Sortis, Abis, Biofast, Trifamox, Anexa, Gabateva, Avodart, Terazosina, Dominans,

Acyclovir is used to decrease pain and speed the healing of sores or blisters in people who have varicella (chickenpox), herpes zoster (shingles; a rash that can occur in people who have had chickenpox in the past), and first-time or repeat outbreaks of genital herpes (a herpes virus infection that causes sores to form around the genitals and rectum from time to time). Acyclovir is also sometimes used to prevent outbreaks of genital herpes in people who are infected with the virus. Acyclovir is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the body. Acyclovir will not cure genital herpes and may not stop the spread of genital herpes to other people.

topical acyclovir adverse effects

Evidence-based, interdisciplinary guidelines for anti-inflammatory treatment of uveitis associated with juvenile idiopathic arthritis. Markers of hepatitis B virus infection in infants born of mothers who are HBs-antigen carriers with anti-HBe present and the problems of passive immunoprophylaxis Development and field-scale optimization of a honeycomb zeolite rotor concentrator/recuperative oxidizer for the abatement of volatile organic carbons from semiconductor industry. Most pancreatic transplants have been placed in diabetic recipients of renal transplants with end-stage renal disease, but application to nonuremic patients not undergoing renal transplants is increasing. These preliminary results suggest that olanzapine monotherapy is effective and relatively safe in patients with treatment-resistant bipolar mania.

acyclovir cream for cold sores dosage for benadryl

Despite the recent advances in the synthesis of this class of natural products, gambieric acids remain unconquered due to their daunting structural complexity, which poses a formidable synthetic challenge to organic chemists. Other characteristic findings were severe hepatic atrophy (right medial, quadrate, left medial, and lateral lobes) with multiple vascular cysts and compensatory hypertrophy of the other lobes. Coil Embolization of Intracranial Aneurysms: A Six-Month Follow-Up Study. The model has been incorporated into a freely available computer program to assist understanding of trainees and others interested in orthotics. There were no general differences in compressive and flexural stress-strain properties between specimens cured according to the methods A and B.

acyclovir eye ointment bp 3 w/w versus

Pediatric pedestrian injuries remain a major cause of childhood death, hospitalization, and disability. To solve this problem, we are developing a liquid-moderator-based neutron spectrometer that is based on the same theory as that of the Bonner sphere spectrometer. The clinical signs of the disease were attenuated in animals stressed before but not after the immune challenge. Based on the auricle biopsy results and the three presenting symptoms (bilateral auricular chondritis, inflammatory arthritis and ocular inflammation), her condition was diagnosed as RP.

acyclovir 400 mg 3 times a day recipes

The knockout of integrin genes in mouse embryos has provided new insights into the function of these receptors during embryonic development and morphogenesis. Three patients required a second incision and they have been asymptomatic for more than 24 months.

acyclovir mechanism of action ppt file

In the conditions we investigated, the molecular sizes of the urinary ALPs were similar as those of original ALPs, except for the enzyme from renal failure. The presence of antibodies to the capsid proteins prevents efficacious adenovirus vector administration in vivo.

acyclovir 800 mg gengar posologia amoxicilina

Gene expression of nitric oxide synthase in cultured human term placental trophoblast during in vitro differentiation. Ordered water structure in an A-DNA octamer at 1.7 A resolution. In addition, the IL-10R1 chain was able to be co-immunoprecipitated with anti-CRF antibody when peripheral blood mononuclear cells were treated with IL-10. An aneurysmal bone cyst was identified in the rib of a 3 1/2-year-old domestic shorthair cat.

acyclovir eye ointment pdf download

Echocardiographic diagnosis of bland thrombus on an aortic valve. Yet, it is unclear whether this may be also true for older children and if so, which component of IVF, i.e. The phenylthiocarbamyl derivatives of common amino acids from protein hydrolysates are separated within 15 min.

vilerm acyclovir 400 mg

The promoter methylation degree of FLNC, THBS1, UCHL1, and DLEC1 in serum could tell the existence of GC and only UCHL1 in the serum was also associated with poor prognosis of GC. Interestingly, Bacillii and Clostridium OTUs correlated with pH and phosphate, which might explain their high abundance across many of the Dutch soils. Apart from the most common etiopathological factors related to cancer, at times very rare causes such as irritant or foreign body induced carcinogenesis is not to be overlooked. Arterial healing in the dog after intraluminal delivery of pulsed Nd-YAG laser energy.

acyclovir 800 mg contraindicaciones

Favorable clinical experience with a phytocolloid in rheumatoid arthritis The high-risk surgical patient: a role for a multi-disciplinary team approach?

acyclovir shingles emedicine treatment

  • acyclovir ointment sizes of diamonds
  • reviews on acyclovir
  • new anti herpes drugs acyclovir
  • acyclovir adalah sale p untuk luka bakar
  • cetirizine 10 mg obat apa acyclovir
  • acyclovir tablets ireland
  • acyclovir pregnancy fda category
  • sogc guidelines herpes pregnancy acyclovir
  • side effects of antiviral drugs acyclovir
  • danovir acyclovir 400 mg
  • acyclovir dose for hsv encephalitis
  • acyclovir on sale
  • clinovir acyclovir medication
  • viral meningitis treatment acyclovir dose in pregnancy
  • dose of acyclovir for herpes labialis
  • acyclovir tablet color
  • acyclovir tablets 200mg 400mg 800mg ibuprofen
  • paralisia de bell tratamento acyclovir dose for chicken
  • colistin renal dose adjustment for acyclovir
  • mucoadhesive tablets for controlled release of acyclovir 800
  • herpes dosage acyclovir
  • acyclovir vs famciclovir vs valacyclovir and pregnancy
  • acyclovir 800 mg espanol yahoo
  • acyclovir side effects on fetus from smoking
  • acyclovir tab 400 mg
  • herpes medication acyclovir reduces shedding
  • acyclovir 800 mg overdose horse
  • acyclovir dosage for outbreak
  • hsv encephalitis acyclovir dose for shingles
  • acyclovir during pregnancy third trimester
  • what is acyclovir 800 mg tablet
  • acyclovir 400 mg tablet reviews
  • orally administered acyclovir for shingles
  • sucralfate drug action of acyclovir
  • generic zovirax acyclovir
  • acyclovir discovery mechanism of action and selectivity bias
  • 400 mg acyclovir for cold sores
  • acyclovir otc equivalent to viagra
  • oxycodone drug action of acyclovir
  • acyclovir treatment for herpes labialis causes
  • acyclovir 400 mg cost at walmart
  • acyclovir dose for ocular herpes contagious
  • acyclovir overdose effects of xanax
  • 400 mg acyclovir once a day
  • crestor drug action of acyclovir
  • dosis tratamiento acyclovir para herpes medication
  • acyclovir shingles pregnancy medication
  • liomont acyclovir dosing
  • measurement of drug action of acyclovir
  • acyclovir treatment for eczema herpeticum eruption
  • herpes ophthalmicus acyclovir dose herpes
  • dose of acyclovir in renal impairment stages
  • calamine drug action of acyclovir
  • acyclovir shingles duration of rash
  • vesicular eruptions following acyclovir administration department
  • cytarabine renal dose adjustment for acyclovir
  • indikasi acyclovir 200mg price
  • acyclovir 200 mg syrupy
  • acyclovir zovirax over the counter
  • acyclovir side effects headache on top
  • acyclovir 400mg tablets price
  • acyclovir 200 mg 5 times daylight
  • acyclovir herpes simplex treatment
  • acyclovir tabletas 400 mg para que sirve
  • dose acyclovir herpes meningitis diagnosis
  • acyclovir price
  • acyclovir medication 800 mg
  • acyclovir suppressive therapy dosage of tylenol
  • acyclovir and pregnancy first trimester
  • valacyclovir vs acyclovir prodrug
  • acyclovir 800 mg gengar posologia aciclovir
  • zovirax acyclovir tablets side
  • declovir acyclovir ointment
  • orally administered acyclovir 200
  • acyclovir treatment for herpes encephalitis
  • acyclovir spray para que sirve

dosing of acyclovir for bell's palsy

We divided 296 patients who had undergone PD and PD with SMPV resection into two groups according to their ages: under or over 70 years old. Molecular basis for species and ligand specificity of a monoclonal antibody raised against human IGF-I. Within the limitations of this study, the present findings reveal differences in the presence of severe depression, nonspecific physical symptoms, and anxiety between the RDC and DC groups. The coated particles of a carbohydrate char and fusinite were characterized in vitro for their size, stability, and pO2 sensitivity. The author examines some of the newly offered ideas and concepts about the interaction of the patient and the analyst.

acyclovir cold sores reviews

A higher number of virus particles were observed in the cytoplasm at 37 degrees C than at 28 degrees C. Optogenetic inhibition of PBelCGRP terminals identified a network of forebrain sites under the control of a PBelCGRP switch that is necessary to arouse animals from hypercapnia. Partial amino acid sequence data of the other subunits allowed us to identify sequence similarity between the 36-kDa protein and fungal TOM40. However, PEG-Fib-IGF treatment resulted in significant improvement of muscle function and structure, as observed histologically.

acyclovir cost at cvs

Sharing clinical photographs: Patient rights, professional ethics, and institutional responsibilities. A comparative study on the alternating mesophilic and thermophilic two-stage anaerobic digestion of food waste.

acyclovir 400 mg tab ranbaxy usa

Whether this remains true in contemporary patients with RA with a high use of disease-modifying and biologic therapy is unknown. The proposed four methodologies are demonstrated and compared using seismic signals recorded by geophones set up on ground surface generated by a surface seismic excitation. Association analysis of TG repeat polymorphism of the neuronal nitric oxide synthase gene with essential hypertension. Degradation products of insulin generated by hepatocytes and by insulin protease.

acyclovir tablets 400mg dose

Steatotic livers are those most commonly rejected for clinical transplantation and are also unsuitable for good quality hepatocyte isolation. Soft-ware-controllable devices and those capable of sensing from both the atria and the ventricles will provide the sophistication necessary for the implementation of complex tachycardia detection algorithms. This cross-sectional study retrospectively reviewed the medical records of patients who were chronically infected with HCV in 2006. To determine the prevalence of nosocomial infection in Auckland Healthcare hospitals.

cravit levofloxacin 500 mg obat apa acyclovir

We failed to isolate a subgroup of early BC patients without LN involvement suitable for PMRT, despite studying a large cohort. This combination of robust features significantly enhances coherence times under realistic conditions and at the same time provides new flexibility in Hamiltonian engineering that otherwise is not achievable. The various surgical approaches for this syndrome are evaluated according to their facility for wide exposure, their potential morbidity, and their beneficial results. Radiotherapy plan evaluation is currently performed by assessing physical parameters, which has many limitations.

factors affecting duration of drug action of acyclovir

Of the 279 individuals who completed baseline measures, 265 completed follow-up measures and are included in these analyses. The genetic results confirm a general pattern of cytonuclear discordance in the focal region. The features that enabled a diagnosis of hysterical paraplegia to be arrived at were: They were predominantly paraplegic, There was a high incidence of previous psychiatric illness and employment in the Health Service or allied professions, Many were actively seeking compensation. Of these 91 patients, 33 received azathioprine/prednisone immunosuppression, whereas cyclosporine/prednisone with or without azathioprine was used in the remaining 58. It predicts separable subgroups among individuals with ADHD, with performance deficits in only one of these domains.

acyclovir 5% ointment 15gmail

It is a powerful bottom-up approach for film fabrication due to the low cost and high efficiency, and is simple and universal for almost all low-dimensional nanostructures. Analogously, Dnmt1 immunodetection and LSCM indicated that the protein was always present and localized in the cytoplasm, regardless the chromatin configuration and the level of global DNA methylation. Ultrasonography for urinary tract evaluation in patients with congenital spine anomalies.

para que sirve el zovirax acyclovir suspension pediatria integral

Several field trials result indicated that ARK-1 was very useful in the field, not only for grapevine but also for various other plant species. This is the first time MALDI-MSI has been applied for three dimensional chemical imaging of a single cell. We investigated feeding-related infection-avoidance strategies in Japanese macaques via field-experimentation and observation. These results suggest that chronically elevated intra-articular levels of IL-1 beta alone are sufficient to produce virtually all the pathologies found in rheumatoid arthritis, and furthermore, demonstrate that gene transfer can be used to investigate the roles of specific gene products in the pathogenesis of arthritis.

acyclovir ideal body weight renal pdf

However, the analysis of insect genomes shows that basal insects contain two SUMO genes, orthologous to vertebrate SUMO1 and SUMO2/3. Results of inhibitor experiments indicated that transcript abundance was regulated primarily by transcription initiation, rather than by degradation. In addition to direct viral cytopathology, the inflammatory response is postulated to contribute to the pathogenesis. Implants that fail because of mechanical stress are colonized by species associated with healthy teeth.

valacyclovir herpes dosage acyclovir

Here, we develop and analyze a dynamical model of CRISPR-mediated prokaryote-phage coevolution that incorporates classical CRISPR kinetics along with the recently discovered infection-induced activation and autoimmunity side effects. Nocturnal ventilatory support in patients with cystic fibrosis: comparison with supplemental oxygen. The collected samples were analyzed using a validated method and found to contain Amp, Meth, MDMA, Coc and BE.

genital herpes acyclovir dose

Next-generation sequencing (NGS) is a genetic technique used to determine the order of nucleotides in DNA. The authors measured the susceptibility of individual spinal root axons to bupivacaine during late pregnancy in rats and compared them with similar measurements in nonpregnant rats.

famciclovir versus acyclovir

A similar effect was found when T-cells were stimulated with PHA. Twenty patients with schizophrenia with a range of SW underwent a functional magnetic resonance imaging (fMRI) reward task. The prevalence of CALR mutations in a cohort of patients with myeloproliferative neoplasms. The transcription factors that control lineage specification of haematopoietic stem cells (HSCs) have been well described for the myeloid and lymphoid lineages, whereas transcriptional control of erythroid (E) and megakaryocytic (Mk) fate is less understood. Not only persistent hyperglycemia but also metabolic, endocrine, and inflammatory effects of obesity and dyslipidemia appear to play an important role in the development of diabetic neuropathy.

lipanthyl supra 160 mg obat apa acyclovir

Our previous reports on the mechanisms involve in the prevention of NEC by glucocorticoids and the reported findings that human recombinant PAF-acetylhydrolase can prevent NEC provide further support for a central role for PAF in NEC development. No significant differences were found in MCC by sexual orientation.

buy acyclovir cream for genital herpes

Pneumococcal disease remains a threat despite an available vaccine. Airport take-off noise assessment aimed at identify responsible aircraft classes. A total of 61 teen parents participated in the design of a structured interview.

acyclovir side effects on fetus while smoking

Responses to both 5-hydroxytryptamine and adrenaline were not blocked in strips which were protected by a high concentration of either 5-hydroxytryptamine or adrenaline throughout exposure to phenoxybenzamine. Activity of acid and alkaline phsophatase in the cerebrospinal fluid. We have used epi-illumination microscopy in vivo to observe the microcirculation directly in secondary lamellae of rainbow trout (Oncorhynchus mykiss) and roach (Rutilus rutilus). Activation of the btl receptor by branchless (bnl), its putative ligand, exerts an instructive role in the process of guiding tracheal cell migration. The Space of Okada with Bilateral Facet Joint Arthrograms During a Lumbar Interlaminar Epidural Injection.

lisovyr acyclovir suspension

This study investigates the treatment expectations and treatment satisfaction of patients with MUS in psychosomatic medicine, biomedicine, and Traditional Chinese Medicine (TCM). Our further phenotyping strengthens the evidence that ANP32B is a widespread regulator of gene expression.

orally administered acyclovir uses

Risk prediction model for major complication after hepatectomy for malignant tumour - A validated scoring system from a university center. Patient satisfaction among Spanish-speaking patients in a public health setting. We advocate the use of large core (14 g) needle breast biopsy over other commonly employed techniques. The silicoater process in a clinical test--results and reasoning from the viewpoint of a 3-year study MicroRNA-target cross-talks: Key players in glioblastoma multiforme.

para que sirve el zovirax acyclovir suspension pediatria

Three separate focus group discussions were held with four nurses, four dietitians and four service assistants engaged in food service. Risk preferences and prenatal exposure to sex hormones for ladinos. The supposition that long-term changes in neuronal properties share molecular pathways with other cells during development and differentiation points towards specific candidate genes as well as towards a general experimental strategy designed to find proteins which might mediate these changes. Our mouse model of CNI reproduces genetic and phenotypic features of the human disease.

metoprolol medication action of acyclovir

It is considered to be harmless both to the patient and the clinical staff, it is easy to apply and there is no discomfort to the patient during the imaging procedure. We demonstrate these capabilities by modeling two multivalent molecules, one representing a ligand and the other a receptor, in a two-dimensional plane (cell membrane). However, the problem with ivermectin is that it is a monotherapy microfilaricide which has limited effect on the adult worm, and thus will need to be continued for the life span of the adult worm, which may last up to 15 years.

acyclovir pastillas 200 mg dosis de diclofenaco

Peak tensile and compressive stresses as well as stent penetration were calculated in the case of an idealized pulmonary artery model having realistic dimensions as well as stiffness. Gingival recession localized to the lower incisors in dental malocclusion

valtrex cold sore dose acyclovir

Great strides have been made in elucidating the mechanisms by which these MHC proteins may bind peptides with diverse sequences and high affinity. Similar structural alterations were seen in endometrium of ectopic pregnancies, and in the decidua parietalis of intrauterine pregnancies.

 Show Hide 
dosage for acyclovir in herpes outbreak 2012-02-05

The results provide the basis for proceeding further study on the biological function of Sjcaspase3 and better understand the apoptosis mechanism of S. The hydroxy-nitrobenzyl (HNB) group attached to a unique tryptophan has been used tamsulosin flomax generic cost in the present study as an extrinsic probe for localization of conformational changes to the heparin-binding region within antithrombin III using immunochemical and spectral techniques.

varicela tratamiento acyclovir dosing 2019-01-14

In this work, experimental and modeling investigations were conducted to examine the effect of biochars pyrolytically produced from municipal solid wastes on removing aqueous As(V) before and after activated by 2M KOH solution. Association Between Early Life Adversity and Risk for Poor Emotional and Physical Health in Adolescence: A Putative Mechanistic Neurodevelopmental Pathway. Objective criteria have been identified that are valid for distinguishing between these two clinical problems. A large number of mutations have been reported in SCO2 (synthesis of cytochrome diclofenac ointment side effects c oxidase) gene in association with COX deficiency reported in different diseases such as cardioencephalomyopathy, cardiomyopathy and Leigh syndrome.

acyclovir dosage for prevention of herpes 2018-08-04

Nitrous oxide impaired electrophysiologic recovery of hippocampal slices after severe hypoxia. We assessed their architecture, mutation and gene expression patterns, response to compounds in culture, and when grown as subcutaneous xenograft tumors in mice. In addition, HIV RNA viral load measurement is becoming increasingly important, mainly for a systematic confirmation of first-line ART failure before switching to second-line treatment to avoid belated as well as premature therapeutic decisions and their potentially negative consequences. Retrospective evaluation of prehospital triage, presentation, interventions and outcome in alliance pharmacy tramadol paediatric drowning managed by a physician staffed helicopter emergency medical service.

herpes simplex 2 treatment acyclovir 400 2013-08-19

Ubr1 is located in the middle of mouse chromosome 2 and in the syntenic 15q15-q21.1 region of human chromosome 15. Bleeding trauma patients were randomized to either a laboratory-driven or a formula-driven (1 plasma:1 platelet:1 RBC) transfusion protocols. In spite of a significant increase in the serum levels of corticosterone, serum testosterone was not significantly affected by diclofenac brand names hyperprolactinaemia. Carcinoembryonic antigen assay in serum and pleural effusion of pulmonary malignancies and benign lesions Here we demonstrate the effects of a high frequency electrical stimulation signal in training cultured networks of cortical neurons.

mucoadhesive tablets for controlled release of acyclovir cream 2015-09-23

Immunohistochemical studies suggested that the metaplasia had arisen in ductular epithelium. No complications were noted during an observation use of axepta tablet magazine period of minimum 12 months.

anti tuberculosis treatment dose acyclovir 2017-01-21

Confocal laser scanning microscopy has shown VIP-like-ir nortriptyline for migraines reviews of movies terminals in close apposition to GnRH-like-ir cell bodies in the lateral septal-preoptic area. Prognostic implications of determining 180 kDa bullous pemphigoid antigen (BPAG2) gene/protein pathology in neonatal junctional epidermolysis bullosa. Noradrenaline and interleukin-1 stimulate CRF secretion from human placental cells in culture Tetramethylpyrazine attenuated OGD-induced TRPC6 downregulation in a tetramethylpyrazine concentration-dependent manner. The combination of structural information, kinetic modeling, and biochemical and electrophysiological experiments provides insight into the mechanism of iGluR gating.

herpetic keratitis treatment acyclovir for shingles 2012-04-07

Time to eye opening, time to following commands, and time to tracheal extubation were shorter in the volatile anesthesia group than the total intravenous anesthesia group. A case of pure gelastic seizures due to hypothalamic hamartoma with a benign course. One-year follow-up for repeat testing and mortality was investigated. Metabolism esperal 500 mg nuspojave klavocina is integral to the pathogenicity of Candida albicans, a major fungal pathogen of humans.

varicella treatment acyclovir dose pediatric 2012-01-31

In recent years, our understanding of the molecular structure of the AIS, its maturation, and its multiple fundamental roles in neuronal function has seen major advances. Darwin (1871) termed this type of natural selection, where differences in reproductive success are labetalol similar drugs to advair caused by competition over mates, sexual selection. Testosterone propionate was more efficient than testosterone in its action on the duration of shell formation. For age, 4 out of 8 studies found inequities and reported less utilization for younger people. The early determination of chorionicity in twin gestations is a critical factor in the management of twin gestations.

acyclovir for recurrent herpes labialis treatment 2011-04-07

Dental maturity has relevance to the interdental spaces and unusual root resorption of mixed dentition. One-step purification of proteins from chicken egg white using counter-current chromatography. The recordings were processed by a Matlab toolbox designed for the analysis and detection of kegunaan difnal k tablets creaky segments, automatically identified using the Kane-Drugman algorithm. We find that the laser field maximally suppresses isomerization if it is both polarized parallel to the excitation dipole and present 50 fs after the initial photoabsorption, at the time when the system is expected to be in the vicinity of a conical intersection that mediates this structural transition.

medicine acyclovir side effects 2014-03-05

Biochemistry, clinical outcome, histopathology, and patient and graft survival data were extracted. The dates of the reviewed records were from 1 January 2008 to 31 December 2008. Age (10, 25 and 40 weeks) did not significantly impact on the effect prazol 20 mg indication synonym of clamping on endothelium-dependent and independent vasoreactivity.