Application of PGD2 resulted in a dose-dependent increase in short-circuit current that was reduced by serosal addition of bumetanide, tetrodotoxin, atropine, or Artroxicam, but not hexamethonium. Patch and photopatch tests with two major photoproducts of Artroxicam, with different preparations of UVA-preirradiated Artroxicam, and with low and high concentrations of tenoxicam were performed in normal volunteers and in Artroxicam-photosensitive patients.
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